"Polypill" for Cardiovascular Disease Prevention
نویسندگان
چکیده
منابع مشابه
The polypill in the primary prevention of cardiovascular disease.
Coronary heart disease (CHD) and stroke are the most common causes of death worldwide. The polypill, a multi-component tablet or capsule designed to reduce several cardiovascular causal risk factors simultaneously, has the potential to reduce the incidence of heart attacks and stroke by about 80%, the precise reduction depending on the formulation of the polypill and adherence to preventive tre...
متن کاملStatins alone or polypill for primary prevention of cardiovascular diseases
Cardiovascular disease (CVD), the leading cause of death and disability worldwide, imposes huge healthcare costs to society and significant burdens to patients. It is estimated that 18 million deaths occurred from CVD annually worldwide [1]. Over three quarters of CVD deaths take place in lowand middle-income countries including Iran. Therefore, developing and implementing public health strateg...
متن کاملProcess evaluation of the impact and acceptability of a polypill for prevention of cardiovascular disease.
IMPORTANCE The Use of a Multidrug Pill In Reducing cardiovascular Events (UMPIRE) trial has shown improved adherence with the use of a polypill strategy when compared with usual medications for cardiovascular disease (CVD) prevention. To advance from efficacy to impact, we need a better understanding of why and how such a strategy might be deployed in complex health systems. OBJECTIVE To unde...
متن کاملA Polypill for primary prevention of cardiovascular disease: A feasibility study of the World Health Organization
BACKGROUND The feasibility of conducting a large-scale Polypill clinical trial in developing countries remains unclear. More information is needed regarding the efficacy in reducing the risk factors of cardiovascular disease (CVD), side effects, improvement in adherence and physician/patient "acceptability" of the Polypill. METHODS We conducted an open-label, parallel-group, randomized clinic...
متن کاملStrengths and Limitations of Using the Polypill in Cardiovascular Prevention
PURPOSE OF REVIEW Polypill and its role in cardiovascular disease (CVD) prevention has been extensively discussed and debated since the inception of the concept in 2003. This article reviews the subsequent accumulated research in this area. RECENT FINDINGS Several short and intermediate to long-term studies with different brands of polypills have analysed the impact of polypill in phase II an...
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ژورنال
عنوان ژورنال: Clinical Diabetes
سال: 2004
ISSN: 0891-8929,0891-8929
DOI: 10.2337/diaclin.22.4.157